Philippus Aureolus Theophrastus Bombastus de Hohenheim celebre dixit: "sola dosis facit venenum". Eum corrigere debemus: "dosis et tempus faciunt venenum". [https://x.com/R34lB0rg/status/1885859866096361741/photo/1](https://x.com/R34lB0rg/status/1885859866096361741/photo/1)

This post not only pays homage to Paracelsus' foundational work but also brings a contemporary update to his philosophy. In today's context, where environmental, occupational, and lifestyle exposures to chemicals are often chronic rather than acute, understanding the role of time in toxicity is crucial. The user's modification to Paracelsus' quote reflects an evolution in toxicological thought, acknowledging that duration of exposure is as critical as the dose in determining health outcomes. This is particularly poignant in discussions around regulatory toxicology, environmental safety regulations, and public health policies where long-term exposure to low levels of pollutants or chemicals is a growing concern. -- Grok